Human leucocyte antigen – G gene polymorphism in laryngeal squamous cell carcinoma patients in Mansoura University Hospitals

This study aimed to detect the genetic association of HLA-G gene polymorphism with LSCC. It was a comparative estimating prevalence both 14-bp insertion versus deletion and HLA-G*01:05 N null allele using PCR-RFLP. highly recorded in patients LSCC (63.0%) whereas (37.0%) lower. The −14/-14 −14/+14 genotypes were significantly higher cases +14/+14 genotype not. found 39 (43.8%) 47 control (52.8%), (p = 0.23). Distribution studied alleles showed no significant correlation clinic-pathological features included cases. There between (versus allele) risk but clear occurrence detected.